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  • Transforming Lives in a Single Dose

    Yannick, 13, was blind before receiving gene therapy, which restored much of his sight.

  • Leadership to Make Gene Therapy a Reality

    Dr. Katherine High has pioneered the development of gene therapy for two decades.

  • Capabilities to Re-Imagine What’s Possible

    Gene therapy is giving Michael, 67, new hope for a life free from hemophilia B.

  • Expanding Life Sciences in Philadelphia

    Spark's west Philadelphia headquarters.

About Spark Therapeutics

We are a leader in the field of gene therapy seeking to transform the lives of patients suffering from debilitating genetic diseases by developing potential one-time, life-altering treatments. Our initial focus is on treating rare diseases where no, or only palliative therapies, exist.


Spark announces successful pivotal Phase 3 trial of SPK-RPE65 for rare, inherited blinding conditions.

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